Symptomatic Lassa virus infection occurs infrequently in West Africa, meaning large vaccine trials are required to measure efficacy. Trials should target children, who are at higher risk of Lassa fever, alongside the further development of targeted school-based health education and household-level risk communication programmes in endemic communities. The high prevalences of malaria co-infection and hearing […]
The Enable Lassa Research Programme (Enable 1.0) Consortium
Introduction of community access to self-tests and antiretroviral drugs through a transition to enabled self-care is very likely to be cost-effective in most settings in east, central, southern, and west Africa; enable incidence declines to be sustained at reduced cost; and increase equity of access to HIV services. Policy makers who wish to consider such […]
Andrew N Phillips, Kenly Sikwese, Valentina Cambiano, Loveleen Bansi-Matharu, Jennifer Smith, Euphemia Sibanda, Cheryl Johnson, Brooke E Nichols, Edinah Mudimu, Frances M Cowan, Paul Revill
As global HIV programmes confront a period of fiscal constraint, the modelling analysis by Andrew Phillips and colleagues1 offers a timely and policy-relevant proposition: that a transition to enabled self-care could sustain, and potentially accelerate, progress towards HIV epidemic control in sub-Saharan Africa. At stake is not only the trajectory of HIV incidence and mortality […]
By 2050, antimicrobial resistance (AMR) is predicted to have caused 40 million deaths globally.1 In the same timeframe, almost 70% of the global population has been projected to be living in urban areas.2 90% of this urbanisation will occur in Africa and Asia, regions most burdened by AMR.3 Urbanisation is linked to an abundance of […]
Rosie Steege, Anne Ngunjiri, Sabina Rashid, Adam P Roberts, Katy Davis, Kate Hawkins, Ralalicia Limato, Joseph Kimani, Clarissa Magdalena, Russell Dacombe, Sally Theobald
This study identified BTC challenges, facilitators, and innovations. The participants described the BTC as fragmented in these settings. The most poignant findings revealed how the lack of blood availability caused profound stress on the health system, contributing to delays, inefficiencies, and worry for patient wellbeing. Innovations encouraged collective stewardship and governance of the BTC, bridging […]
Linda S Barnes, Jennifer Makin, Jose R Paiz, Jana Macleod, Cindy Mical Makanga, Tecla Kivuli Chelagat, Alejandro Munoz-Valencia, Ejemai Eboreime, Robert Kamu Kaburu, Abdirahman Musa, Carolyne Njoki, Cavin Otieno Opiyo, Kristina E Rudd, Mark Yazer, Bopaya Bidanda, Juan Carlos Puyana, Pratap Kumar