In their systematic review and Bayesian network meta-analysis on postpartum haemorrhage prophylaxis in caesarean deliveries (August, 2025), Amaral and colleagues1 reported risk ratios (95% credible intervals) of 0·44 (0·33–0·58) for oxytocin plus tranexamic acid versus oxytocin alone and 0·54 (0·37–0·74) for carbetocin versus oxytocin alone. Although informative, the systematic review raises several methodological concerns.
Yoshihide Inayama, Toshiaki A Furukawa, Yoshitsugu Chigusa, Masaki Mandai
We appreciate the interest shown by Yoshihide Inayama and colleagues1 in our Article2 and are grateful for their meticulous assessment of our statistical analyses. As such, we want to address their concerns regarding possible publication bias and inappropriate labelling of one of the included studies.
Education policies significantly reduced offspring mortality in LMICs, with greater benefits for populations with lower household wealth. Modelling indicated that interruptions to educational instruction time led to a substantial increase in offspring mortality. There is a critical need for policies to mitigate educational disruptions to prevent offspring deaths.
Zhihui Li, Ning Ma, Shaoru Chen, Shang Lou, Guangyu Tong, Wei Huang, Justice Moses K Aheto, Melkamu Aderajew Zemene, Md Ashfikur Rahman, Abdallah Mkopi, Peter Karoli, John Lapah Niyi, Chunling Lu, S V Subramanian, Pascal Geldsetzer, Sebastian Vollmer, Margaret Chan Fung Fu-Chun, Rifat Atun
Global adoption of sugar-sweetened beverage taxes has rapidly accelerated since 1990; however, there is important heterogeneity by region and tax structure, and the taxes are shaped by a country's economic capacity, social development, and health conditions.
Lizbeth Moreno Loaeza, Laura Lara-Castor, Julia R Sharib, Frederick Cudhea, Meng Wang, Peizhi Li, Dariush Mozaffarian, on behalf of the Global Dietary Database collaborators
Amaral S, Provinciatto H, Gewehr DM, et al. Prophylactic strategies for prevention of postpartum haemorrhage in caesarean delivery: a systematic review and Bayesian network meta-analysis of randomised controlled trials. Lancet Glob Health 2025; 13: e1415–24—In this Article, the control group in one included study (Pacheco LD, Clifton RG, Saade GR, et al. N Engl J […]